Hexosaminidase A Antikörper (C-Term)

Produktnummer ABIN926663

Der Kaninchen Polyklonal Anti-Hexosaminidase A-Antikörper wurde für WB validiert. Er ist geeignet, Hexosaminidase A in Proben von Human zu detektieren.

Kurzübersicht für Hexosaminidase A Antikörper (C-Term) (ABIN926663)

Target: Hexosaminidase A (HEXA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hexosaminidase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Hexosaminidase A Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: HEXA antibody was raised in rabbit using the C terminal of HEXA as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

HEXA Blocking Peptide, (ABIN5613994), is also available for use as a blocking control in assays to test for specificity of this HEXA antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Hexosaminidase A

Target: Hexosaminidase A (HEXA)

Andere Bezeichnung: HEXA

Hintergrund: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Synonyms: Polyclonal HEXA antibody, Anti-HEXA antibody, hexosaminidase A, alpha polypeptide antibody, MGC99608 antibody, TSD antibody.

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process