Vinculin Antikörper (C-Term)

Produktnummer ABIN926662

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Vinculin in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Vinculin Antikörper (C-Term) (ABIN926662)

Target: Vinculin (VCL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vinculin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Vinculin Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: VCL antibody was raised in rabbit using the C terminal of VCL as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

VCL Blocking Peptide, (ABIN5616950), is also available for use as a blocking control in assays to test for specificity of this VCL antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Vinculin

Target: Vinculin (VCL)

Andere Bezeichnung: VCL

Hintergrund: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Synonyms: Polyclonal VCL antibody, Anti-VCL antibody, vinculin antibody, CMD1W antibody, CMH15 antibody, MVCL antibody.

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2