NAPA Antikörper (N-Term)

Produktnummer ABIN926040

Dieses Anti-NAPA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NAPA in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für NAPA Antikörper (N-Term) (ABIN926040)

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAPA Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Zebrafisch (Brachydanio rerio)

Immunogen: NAPA antibody was raised in rabbit using the N terminal of NAPA as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

NAPA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NAPA antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NAPA

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Andere Bezeichnung: NAPA

Hintergrund: The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. Synonyms: Polyclonal NAPA antibody, Anti-NAPA antibody, N-ethylmaleimide-sensitive factor attachment protein, alpha antibody.

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization