NAPA Antikörper (N-Term)

Produktnummer ABIN926040

Der Kaninchen Polyklonal anti-NAPA Antikörper (ABIN926040) detektiert spezifisch NAPA in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für NAPA Antikörper (N-Term) (ABIN926040)

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAPA Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Zebrafisch (Brachydanio rerio)

Immunogen: NAPA antibody was raised in rabbit using the N terminal of NAPA as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

NAPA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NAPA antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NAPA

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Andere Bezeichnung: NAPA

Hintergrund: The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. Synonyms: Polyclonal NAPA antibody, Anti-NAPA antibody, N-ethylmaleimide-sensitive factor attachment protein, alpha antibody.

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization