TIAL1 Antikörper (C-Term)

Produktnummer ABIN925990

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TIAL1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für TIAL1 Antikörper (C-Term) (ABIN925990)

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIAL1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Hund, Maus, Ratte (Rattus), Huhn, Frosch, Zebrafisch (Brachydanio rerio)

Immunogen: TIAL1 antibody was raised in rabbit using the C terminal of TIAL1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TIAL1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TIAL1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TIAL1

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Andere Bezeichnung: TIAL1

Hintergrund: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif. Synonyms: Polyclonal TIAL1 antibody, Anti-TIAL1 antibody, TIA1 cytotoxic granule-associated RNA binding protein-like 1 antibody.