ACTN2 Antikörper (C-Term)

Produktnummer ABIN925860

Produktdetails anti-ACTN2 Antikörper

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte (Rattus), Human, Rind (Kuh), Hund, Huhn, Zebrafisch (Brachydanio rerio), Frosch

Immunogen: ACTN2 antibody was raised in rabbit using the C terminal of ACTN2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ACTN2 Blocking Peptide, catalog no. 33R-4126, is also available for use as a blocking control in assays to test for specificity of this ACTN2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu ACTN2

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Andere Bezeichnung: ACTN2 (ACTN2 Produkte)

Synonyme: MGC89234 antikoerper, ACTN2 antikoerper, 1110008F24Rik antikoerper, CMD1AA antikoerper, wu:fd44c03 antikoerper, zgc:123223 antikoerper, actinin alpha 2 antikoerper, actinin, alpha 2b antikoerper, actinin alpha 2 S homeolog antikoerper, actn2 antikoerper, ACTN2 antikoerper, Actn2 antikoerper, actn2b antikoerper, actn2.S antikoerper

Hintergrund: The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function. Synonyms: Polyclonal ACTN2 antibody, Anti-ACTN2 antibody.

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity