ACTN2 Antikörper (C-Term)

Produktnummer ABIN925860

Dieser Anti-ACTN2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ACTN2 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für ACTN2 Antikörper (C-Term) (ABIN925860)

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACTN2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Ratte (Rattus), Human, Rind (Kuh), Hund, Huhn, Zebrafisch (Brachydanio rerio), Frosch

Immunogen: ACTN2 antibody was raised in rabbit using the C terminal of ACTN2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ACTN2 Blocking Peptide, (ABIN939512), is also available for use as a blocking control in assays to test for specificity of this ACTN2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu ACTN2

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Andere Bezeichnung: ACTN2

Hintergrund: The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function. Synonyms: Polyclonal ACTN2 antibody, Anti-ACTN2 antibody.

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity