PROCR Antikörper

Produktnummer ABIN920711

Produktdetails anti-PROCR Antikörper

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PROCR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Spezifität: The rat monoclonal antibody LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein over-expressed in several human non-Pgp multidrug-resistant (MDR) tumor cell lines. LMR-42 has potential value for the detection of EPCR, which may mediate anti-coagulant and anti-inflammatory functions along vascular endothelia. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug-resistance is unclear.

Immunogen: Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein C receptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC).

Klon: LMR-42

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: Use at a 1:20 dilution on frozen sections, air-dried or acetone fixed cells. Flow cytometry: No cell permeabilization required.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 mL antibody (>200 tests) at 100 µg IgG/mL in serum-free culture supernatant with protein stabilizer and 0.1% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Andere Bezeichnung: Endothelial Cell Protein C Receptor (PROCR Produkte)