4-Hydroxy-2-Hexenal (4-HHE) Antikörper

Produktnummer ABIN920668

Dieser Maus Monoklonal Antikörper detektiert spezifisch 4-Hydroxy-2-Hexenal (4-HHE) in IHC.

Kurzübersicht für 4-Hydroxy-2-Hexenal (4-HHE) Antikörper (ABIN920668)

Target: 4-Hydroxy-2-Hexenal (4-HHE)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: HHE53

Produktdetails

Spezifität: Specific for HHE-modified protein (especially HHE-His Michael adduct)

Aufreinigung: Protein A purified.

Immunogen: HHE-modified keyhole-lympet hemocyanine.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: Recommended antibody concentration is 0.5 - 1.0 µg/mL on paraformaldehyde fixed tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Monoclonal antibody at 100 µg/mL in 10 mM PBS containing 0.1 % NaN3 and protein stabilizer. Prepared as ascite.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Antigendetails

Target: 4-Hydroxy-2-Hexenal (4-HHE)

Substanzklasse: Chemical

Hintergrund: 4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is a highly reactive aldehyde and reacts with histidine residue of protein to form Michael- addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enables detection of HHE-His in tissue samples.