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TXN2 Antikörper (AA 101-166) (AbBy Fluor® 555)

This anti-TXN2 antibody (ABIN917568) is a Rabbit Polyclonal antibody detecting TXN2 in WB, IF (cc), IF (p). Suitable for Rat.
Produktnummer ABIN917568

Kurzübersicht für TXN2 Antikörper (AA 101-166) (AbBy Fluor® 555) (ABIN917568)

Target

Alle TXN2 Antikörper anzeigen
TXN2 (Thioredoxin 2 (TXN2))

Reaktivität

  • 36
  • 25
  • 11
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Ratte

Wirt

  • 51
  • 3
Kaninchen

Klonalität

  • 48
  • 6
Polyklonal

Konjugat

  • 29
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TXN2 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 47
  • 20
  • 16
  • 14
  • 12
  • 12
  • 12
  • 8
  • 6
  • 5
  • 3
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 15
    • 14
    • 8
    • 6
    • 3
    • 1
    AA 101-166

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Pig,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Thioredoxin 2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    TXN2 (Thioredoxin 2 (TXN2))

    Andere Bezeichnung

    Thioredoxin 2

    Hintergrund

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    Gen-ID

    25828

    Pathways

    Cell RedoxHomeostasis
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