SRRM1 Antikörper (AA 21-120) (FITC)

Produktnummer ABIN916453

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SRRM1 in WB, IF (cc) und IF (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SRRM1 Antikörper (AA 21-120) (FITC) (ABIN916453)

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRRM1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SRRM1 Antikörper (FITC)

Bindungsspezifität: AA 21-120

Verwendungszweck: SRRM1 Polyclonal Antibody, FITC Conjugated

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRRM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-1000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Andere Bezeichnung: SRRM1

Hintergrund:

Synonyms: Ser/Arg related nuclear matrix protein, Ser/Arg-related nuclear matrix protein, Serine/arginine repetitive matrix protein 1, SR related nuclear matrix protein of 160 kDa, SR-related nuclear matrix protein of 160 kDa, SRm160, Srrm1, SRRM1_HUMAN.

Background: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Gen-ID: 10250