RACGAP1 Antikörper (AA 301-400) (HRP)

Produktnummer ABIN912800

Der Kaninchen Polyklonal Anti-RACGAP1-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, RACGAP1 in Proben von Ratte zu detektieren.

Kurzübersicht für RACGAP1 Antikörper (AA 301-400) (HRP) (ABIN912800)

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RACGAP1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RACGAP1 Antikörper (HRP)

Bindungsspezifität: AA 301-400

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RACGAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Andere Bezeichnung: RACGAP1

Hintergrund:

Synonyms: GAP, Gap1, GTPase activating protein, HsCYK 4, HsCYK4, ID GAP, KIAA1478, MgcRacGAP, Rac GTPase activating protein 1, RACGAP 1, RGAP1_HUMAN.

Background: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Gen-ID: 29127

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor