SPDEF/PSE Antikörper (AA 251-335) (AbBy Fluor® 488)

Produktnummer ABIN910490

Der Kaninchen Polyklonal Anti-SPDEF/PSE-Antikörper wurde für FACS, IF (cc) und IF (p) validiert. Er ist geeignet, SPDEF/PSE in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SPDEF/PSE Antikörper (AA 251-335) (AbBy Fluor® 488) (ABIN910490)

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPDEF/PSE Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SPDEF/PSE Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 251-335

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDEF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPDEF/PSE

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Andere Bezeichnung: Pdef/Spdef

Hintergrund:

Synonyms: bA375E1.3, PDEF, Prostate derived Ets factor, PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR, Prostate epithelium-specic Ets transcription factor, Prostate specic Ets, Prostate-derived Ets factor, Prostate-specic Ets, PSE, RP11-375E1__A.3, SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR, SAM pointed domain-containing Ets transcription factor, Spdef, SPDEF_HUMAN.

Background: SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.

Gen-ID: 25803