DPH1 Antikörper (AA 251-350) (AbBy Fluor® 647)
Kurzübersicht für DPH1 Antikörper (AA 251-350) (AbBy Fluor® 647) (ABIN909600)
Target
Alle DPH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 251-350
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Cow,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human OVCA1
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- DPH1 (DPH1 Homolog (DPH1))
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Andere Bezeichnung
- OVCA1
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Hintergrund
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Synonyms: Candidate tumor suppressor in ovarian cancer 1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog like 1, Diphthamide biosynthesis protein 2 like, Diptheria toxin resistance protein required for diphthamide biosynthesis Saccharomyces like 1 , Diptheria toxin resistance protein required for diphthamide biosynthesis like 1, DPH like 1 S. cerevisiae, DPH like 1, DPH1, DPH1 homolog S. cerevisiae, DPH1 homolog, DPH2 like 1, DPH2L, DPH2L1, HsDph1, Ovarian cancer associated gene 1, Ovarian cancer associated gene 1 protein, Ovarian tumor suppressor candidate 1, DPH1_HUMAN.
Background: OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.
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Gen-ID
- 1801
Target
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