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Neuropilin 1 Antikörper (AA 851-923) (AbBy Fluor® 350)

Dieses Anti-Neuropilin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Neuropilin 1 in WB, IF (cc) und IF (p). Geeignet für Human und Ratte.
Produktnummer ABIN908967

Kurzübersicht für Neuropilin 1 Antikörper (AA 851-923) (AbBy Fluor® 350) (ABIN908967)

Target

Alle Neuropilin 1 (NRP1) Antikörper anzeigen
Neuropilin 1 (NRP1)

Reaktivität

  • 124
  • 65
  • 61
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 123
  • 40
  • 7
  • 4
  • 1
Kaninchen

Klonalität

  • 116
  • 59
Polyklonal

Konjugat

  • 89
  • 22
  • 17
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Neuropilin 1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation

  • 127
  • 69
  • 47
  • 41
  • 36
  • 36
  • 14
  • 14
  • 13
  • 10
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-923

    Kreuzreaktivität

    Human, Ratte

    Homologie

    Mouse,Sheep,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human neuropilin-1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Neuropilin 1 (NRP1)

    Andere Bezeichnung

    Neuropilin 1

    Hintergrund

    Synonyms: NP1, NRP, BDCA4, CD304, VEGF165R, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, NRP1

    Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

    Gen-ID

    8829

    UniProt

    O14786

    Pathways

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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