NME5 Antikörper (AA 81-150) (Cy5)

Produktnummer ABIN908533

Produktdetails anti-NME5 Antikörper (Cy5)

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Bindungsspezifität: AA 81-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NME5 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NME5/IPIA beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NME5

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Andere Bezeichnung: NME5 (NME5 Produkte)

Hintergrund:

Synonyms: Inhibitor of p53 induced apoptosis beta, IPIA beta, NDK-H 5, NDP kinase homolog 5, NM23 H5, Nm23-M5, NM23H5, Non-metastatic cells 5, protein expressed in nucleoside-diphosphate kinase, Nonmetastatic cells 5, protein expressed in, Nonmetastatic protein 23, homolog 5, Nucleoside diphosphate kinase homolog 5, RSPH23, Testis specic nm23 homolog, NDK5_HUMAN.

Background: NME5 does not seem to have NDK kinase activity but confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. It may play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. NME5 is specifically expressed in testis germinal cells.

Gen-ID: 8382

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling