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Nkx2.5/ Cardiac-Specic Homeobox 1 (AA 85-180) Antikörper (Biotin)

Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN908433
  • Target
    Nkx2.5/ Cardiac-Specic Homeobox 1
    Bindungsspezifität
    AA 85-180
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Applikation
    • 13
    • 13
    • 12
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Nkx2.5
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Nkx2.5/ Cardiac-Specic Homeobox 1
    Andere Bezeichnung
    Nkx2.5/Cardiac-specic homeobox 1
    Synonyme
    Csx antikoerper, Nkx-2.5 antikoerper, Nkx2.5 antikoerper, tinman antikoerper, NK2 homeobox 5 antikoerper, Nkx2-5 antikoerper
    Hintergrund

    Synonyms: Csx, Nkx2.5, tinman, Nkx-2.5, Homeobox protein Nkx-2.5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, Nkx2-5, Nkx2e

    Background: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.

    Gen-ID
    18091
    UniProt
    P42582
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