KARS Antikörper (AA 301-400) (AbBy Fluor® 350)

Produktnummer ABIN903370

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KARS in WB, IF (p) und IF (cc). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KARS Antikörper (AA 301-400) (AbBy Fluor® 350) (ABIN903370)

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KARS Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-KARS Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 301-400

Verwendungszweck: Lysyl tRNA synthetase Antibody, AbBy Fluor-350 Conjugated

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KARS2/Lysyl tRNA syntase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-1000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Andere Bezeichnung: Lysyl tRNA synthetase

Hintergrund:

Synonyms: KARS 2, KARS, KARS2, KIAA0070, KRS, Lysine tRNA ligase, Lysine--tRNA ligase, LysRS, Lysyl-tRNA synthetase, SYK_HUMAN.

Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.

Gen-ID: 6850