BAIAP2 Antikörper (AA 151-250) (AbBy Fluor® 350)

Produktnummer ABIN903103

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BAIAP2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für BAIAP2 Antikörper (AA 151-250) (AbBy Fluor® 350) (ABIN903103)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-BAIAP2 Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRS P53

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Andere Bezeichnung: BAIAP2

Hintergrund:

Synonyms: Insulin receptor substrate P53, IRSp53, IRS P53, IRS-P53, Baiap2, BAI1 associated protein 2 isoform 3, Brain-specic angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Insulin receptor tyrosine kinase substrate protein p53, Insulin receptor substrate p53, Insulin receptor substrate protein of 53 kDa, IRSp53, BAIP2_HUMAN, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, FLAF3, IRS-58, IRSp53/58.

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.

Gen-ID: 10458