ILP-2 Antikörper (AA 141-236) (Cy5)
Kurzübersicht für ILP-2 Antikörper (AA 141-236) (Cy5) (ABIN902643)
Target
Alle ILP-2 (BIRC8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 141-236
- 
                                            Kreuzreaktivität
- Ratte
- 
                                            Homologie
- Human,Mouse,Chicken,Rabbit
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human ILP2
- 
                                            Isotyp
- IgG
 
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- 
    
- 
    - 
                                            Applikationshinweise
- 
                        IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
- 
                                            Andere Bezeichnung
- ILP2
- 
                                            Hintergrund
- 
                        Synonyms: Baculoviral IAP repeat containing 8, Baculoviral IAP repeat containing protein 8, Baculoviral IAP repeat-containing protein 8, BIRC 8, BIRC8, BIRC8 protein, BIRC8_HUMAN, hILP 2, hILP2, IAP like protein 2, IAP-like protein 2, ILP 2, ILP-2, Inhibitor of apoptosis like protein 2, Inhibitor of apoptosis-like protein 2, Testis specic inhibitor of apoptosis, Testis-specic inhibitor of apoptosis. Background: Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9. 
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                                            Gen-ID
- 112401
 Target
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