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ILP-2 Antikörper (AA 141-236) (HRP)

This anti-ILP-2 antibody (ABIN902635) is a Rabbit Polyclonal antibody detecting ILP-2 in ELISA, IHC (fro), IHC (p). Suitable for Rat.
Produktnummer ABIN902635

Kurzübersicht für ILP-2 Antikörper (AA 141-236) (HRP) (ABIN902635)

Target

Alle ILP-2 (BIRC8) Antikörper anzeigen
ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))

Reaktivität

  • 19
  • 10
  • 6
Ratte

Wirt

  • 22
  • 2
Kaninchen

Klonalität

  • 24
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ILP-2 Antikörper ist konjugiert mit HRP

Applikation

  • 13
  • 13
  • 9
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 4
    • 3
    • 1
    AA 141-236

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ILP2

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))

    Andere Bezeichnung

    ILP2

    Hintergrund

    Synonyms: Baculoviral IAP repeat containing 8, Baculoviral IAP repeat containing protein 8, Baculoviral IAP repeat-containing protein 8, BIRC 8, BIRC8, BIRC8 protein, BIRC8_HUMAN, hILP 2, hILP2, IAP like protein 2, IAP-like protein 2, ILP 2, ILP-2, Inhibitor of apoptosis like protein 2, Inhibitor of apoptosis-like protein 2, Testis specic inhibitor of apoptosis, Testis-specic inhibitor of apoptosis.

    Background: Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

    Gen-ID

    112401
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