IER3 Antikörper (PE)

Produktnummer ABIN901746

Dieses Anti-IER3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IER3 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für IER3 Antikörper (PE) (ABIN901746)

Target: IER3 (Immediate Early Response 3 (IER3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IER3 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-IER3 Antikörper (PE)

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IER3

Target: IER3 (Immediate Early Response 3 (IER3))

Andere Bezeichnung: IEX1

Hintergrund:

Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3

Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

Molekulargewicht: 17kDa

Gen-ID: 8870

UniProt: P46695

Pathways: Regulation of Carbohydrate Metabolic Process