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IER3 Antikörper (AA 85-156) (Cy7)

This anti-IER3 antibody (ABIN901744) is a Rabbit Polyclonal antibody detecting IER3 in WB, IF (cc), IF (p). Suitable for Rat.
Produktnummer ABIN901744

Kurzübersicht für IER3 Antikörper (AA 85-156) (Cy7) (ABIN901744)

Target

Alle IER3 Antikörper anzeigen
IER3 (Immediate Early Response 3 (IER3))

Reaktivität

  • 33
  • 18
  • 15
  • 4
  • 4
  • 4
Ratte

Wirt

  • 46
  • 1
Kaninchen

Klonalität

  • 46
  • 1
Polyklonal

Konjugat

  • 13
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IER3 Antikörper ist konjugiert mit Cy7

Applikation

  • 36
  • 18
  • 14
  • 12
  • 12
  • 12
  • 11
  • 8
  • 6
  • 3
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 85-156

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IER3 (Immediate Early Response 3 (IER3))

    Andere Bezeichnung

    IEX1

    Hintergrund

    Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3

    Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

    Gen-ID

    8870

    UniProt

    P46695

    Pathways

    Regulation of Carbohydrate Metabolic Process
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