ERCC6L Antikörper (AA 301-400) (Cy5.5)

Produktnummer ABIN895658

Produktdetails anti-ERCC6L Antikörper

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Bindungsspezifität: AA 301-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC6L Antikörper ist konjugiert mit Cy5.5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERCC6L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu ERCC6L

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Andere Bezeichnung: ERCC6L (ERCC6L Produkte)

Synonyme: PICH antikoerper, RAD26L antikoerper, BC004701 antikoerper, D330021P09Rik antikoerper, RGD1565734 antikoerper, fc22h03 antikoerper, si:ch211-278b8.3 antikoerper, wu:fc22h03 antikoerper, ERCC excision repair 6 like, spindle assembly checkpoint helicase antikoerper, excision repair cross-complementing rodent repair deficiency complementation group 6 like antikoerper, DNA excision repair protein ERCC-6-like antikoerper, excision repair cross-complementation group 6-like antikoerper, ERCC6L antikoerper, Ercc6l antikoerper, LOC100373376 antikoerper, LOC100494766 antikoerper, LOC100552957 antikoerper, LOC100560751 antikoerper, LOC100563247 antikoerper, ercc6l antikoerper

Hintergrund:

ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.

Subcellular location: Nucleus

Synonyms: ATP dependent helicase ERCC6 like, DNA excision repair protein ERCC 6 like, ERCC 6L, ERCC6L, Excision repair cross complementing rodent repair deficiency complementation group 6 like, Excision repair protein ERCC6 like, FLJ20105, MGC131695, PICH, Plk1 interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ HCC 15, ERC6L_HUMAN.

Gen-ID: 54821