ERCC6L Antikörper (AA 301-400) (Cy5.5)
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- Target Alle ERCC6L Antikörper anzeigen
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERCC6L Antikörper ist konjugiert mit Cy5.5
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ERCC6L
- Isotyp
- IgG
- Top Product
- Discover our top product ERCC6L Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
- Andere Bezeichnung
- ERCC6L (ERCC6L Produkte)
- Hintergrund
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Synonyms: ATP dependent helicase ERCC6 like, DNA excision repair protein ERCC 6 like, ERCC 6L, ERCC6L, Excision repair cross complementing rodent repair deficiency complementation group 6 like, Excision repair protein ERCC6 like, FLJ20105, MGC131695, PICH, Plk1 interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ HCC 15, ERC6L_HUMAN.
Background: ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
- Gen-ID
- 54821
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