DUSP7 Antikörper (AA 321-419) (Alexa Fluor 647)

Produktnummer ABIN894609

Produktdetails anti-DUSP7 Antikörper

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Bindungsspezifität: AA 321-419

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP7 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu DUSP7

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Andere Bezeichnung: DUSP7 (DUSP7 Produkte)

Synonyme: DUSP7 antikoerper, mkpx antikoerper, mkp-x antikoerper, pyst2 antikoerper, MKPX antikoerper, PYST2 antikoerper, AU015694 antikoerper, Mkpx antikoerper, Pyst2 antikoerper, mkp-X antikoerper, dual specificity phosphatase 7 antikoerper, Dual specificity protein phosphatase 7 antikoerper, DUSP7 antikoerper, dusp7 antikoerper, dus7 antikoerper, Dusp7 antikoerper

Hintergrund:

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses

Subcellular location: Cytoplasm

Synonyms: Dual specicity phosphatase 7, Dual specicity protein phosphatase 7, Dual specicity protein phosphatase PYST2, DUS7_HUMAN, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MKPX, PYST2.

Gen-ID: 1849

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades