DLK1 Antikörper (AA 251-350) (AbBy Fluor® 350)

Produktnummer ABIN894075

Produktdetails anti-DLK1 Antikörper (AbBy Fluor® 350)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Bindungsspezifität: AA 251-350

Reaktivität: Human, Maus, Ratte, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLK1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte, Schaf

Homologie: Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse DLK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Andere Bezeichnung: Dlk1 (DLK1 Produkte)

Hintergrund:

Synonyms: DLK, FA1, ZOG, pG2, DLK-1, PREF1, Delta1, Pref-1, Protein delta homolog 1, DLK1

Background: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].

Gen-ID: 8788

UniProt: P80370