CCAR1 Antikörper (AA 731-830) (Cy7)

Produktnummer ABIN894031

Produktdetails anti-CCAR1 Antikörper

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Bindungsspezifität: AA 731-830

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCAR1 Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DIS/CCAR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Andere Bezeichnung: CCAR1 (CCAR1 Produkte)

Synonyme: CCAR1 antikoerper, KIAA1967 antikoerper, ccar1 antikoerper, MGC81663 antikoerper, zehn1480 antikoerper, hm:zehn1480 antikoerper, si:dkey-85g17.2 antikoerper, RP11-437A18.1 antikoerper, CARP-1 antikoerper, 2610511G16Rik antikoerper, 9430036H15Rik antikoerper, Carp1 antikoerper, RGD1560358 antikoerper, cell division cycle and apoptosis regulator 1 antikoerper, cell division cycle and apoptosis regulator 1 L homeolog antikoerper, cell division cycle and apoptosis regulator protein 1 antikoerper, CCAR1 antikoerper, ccar1.L antikoerper, LOC5575286 antikoerper, ccar1 antikoerper, LOC409891 antikoerper, Ccar1 antikoerper

Hintergrund:

Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.

Subcellular location: Cytoplasm

Synonyms: CARP-1, Carp1, CCAR1, CCAR1_HUMAN, Cell cycle and apoptosis regulatory protein 1, cell division cycle and apoptosis regulator 1, Cell division cycle and apoptosis regulator protein 1, Death Inducer with SAP domain, FLJ10590, FLJ10839, FLJ13376, FLJ20734, MGC7730, RP11-437A18.1.

Gen-ID: 55749