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CSMD2 Antikörper (AA 251-350) (Cy3)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CSMD2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN892429

Kurzübersicht für CSMD2 Antikörper (AA 251-350) (Cy3) (ABIN892429)

Target

CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Reaktivität

  • 18
  • 10
  • 4
  • 4
  • 4
  • 4
Maus

Wirt

  • 24
Kaninchen

Klonalität

  • 24
Polyklonal

Konjugat

  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CSMD2 Antikörper ist konjugiert mit Cy3

Applikation

  • 19
  • 12
  • 12
  • 7
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 5
    • 1
    AA 251-350

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Cow,Sheep,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CSMD2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

    Andere Bezeichnung

    CSMD2

    Hintergrund

    Synonyms: CSMD2, CSMD2_HUMAN, CUB and Sushi SCR repeat domain, CUB and sushi domain-containing protein 2, CUB and sushi multiple domains protein 2, dJ1007G16.1, dJ1007G16.2, dJ947L8.1, KIAA1884.

    Background: The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.

    Gen-ID

    114784
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