COMMD1 Antikörper (AA 95-190) (Biotin)
Kurzübersicht für COMMD1 Antikörper (AA 95-190) (Biotin) (ABIN891771)
Target
Alle COMMD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 95-190
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Cow,Sheep,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human COMMD1/MURR1
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
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Andere Bezeichnung
- COMMD1
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Hintergrund
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Synonyms: C2orf5, COMD1, COMD1_HUMAN, COMM domain-containing protein 1, COMMD1, copper metabolism domain containing 1, MGC27155, MURR1, Protein Murr1.
Background: Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
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Gen-ID
- 150684
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Pathways
- Transition Metal Ion Homeostasis
Target
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