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CIDEC Antikörper (AA 101-200) (Cy5)

CIDEC Reaktivität: Human, Maus, Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN890721
$470.46
Zzgl. Versandkosten $50.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle CIDEC Antikörper anzeigen
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 40
    • 5
    • 1
    Kaninchen
    Klonalität
    • 43
    • 3
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CIDEC Antikörper ist konjugiert mit Cy5
    Applikation
    • 32
    • 22
    • 12
    • 12
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology.
    Homologie
    Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CIDEC
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Andere Bezeichnung
    CIDEC (CIDEC Produkte)
    Synonyme
    fsp27 antikoerper, cide-3 antikoerper, MGC89274 antikoerper, cidec antikoerper, MGC82483 antikoerper, CIDEC antikoerper, fd36c01 antikoerper, wu:fd36c01 antikoerper, zgc:153033 antikoerper, CIDE-3 antikoerper, CIDE3 antikoerper, FPLD5 antikoerper, FSP27 antikoerper, Fsp27 antikoerper, CIDE-C antikoerper, cell death inducing DFFA like effector c antikoerper, cell death inducing DFFA like effector c S homeolog antikoerper, cell death-inducing DFFA-like effector c antikoerper, Cell death activator CIDE-3 antikoerper, cidec antikoerper, cidec.S antikoerper, CIDEC antikoerper, Cidec antikoerper
    Hintergrund

    Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: CIDE3, FPLD5, FSP27, CIDE-3, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC

    Gen-ID
    63924
    UniProt
    Q96AQ7
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