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CIDEC Antikörper (AA 101-200) (Cy3)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CIDEC in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN890716

Kurzübersicht für CIDEC Antikörper (AA 101-200) (Cy3) (ABIN890716)

Target

Alle CIDEC Antikörper anzeigen
CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Reaktivität

Human, Maus, Ratte

Wirt

  • 40
  • 5
  • 1
Kaninchen

Klonalität

  • 43
  • 3
Polyklonal

Konjugat

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CIDEC Antikörper ist konjugiert mit Cy3

Applikation

  • 37
  • 16
  • 12
  • 12
  • 10
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Spezifität

    Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology.

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CIDEC

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

    Andere Bezeichnung

    CIDEC

    Hintergrund

    Synonyms: CIDE3, FPLD5, FSP27, CIDE-3, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC

    Background: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

    Gen-ID

    63924

    UniProt

    Q96AQ7
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