CETP Antikörper (AA 355-450) (AbBy Fluor® 647)

Produktnummer ABIN890261

Der Kaninchen Polyklonal Anti-CETP-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CETP in Proben von Maus zu detektieren.

Kurzübersicht für CETP Antikörper (AA 355-450) (AbBy Fluor® 647) (ABIN890261)

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CETP Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CETP Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 355-450

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CETP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Andere Bezeichnung: CETP

Hintergrund:

Synonyms: BPF, CETP, CETP_HUMAN, Cholesteryl ester transfer, Cholesteryl ester transfer protein, Cholesteryl ester transfer protein plasma, Cholesteryl ester transfer protein precursor, HDLCQ10, Lipid transfer protein I.

Background: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Gen-ID: 1071