CDO1 Antikörper (AA 101-200) (Alexa Fluor 647)

Produktnummer ABIN889875

Produktdetails anti-CDO1 Antikörper

Target: CDO1 (Cysteine Dioxygenase, Type I (CDO1))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDO1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu CDO1

Target: CDO1 (Cysteine Dioxygenase, Type I (CDO1))

Andere Bezeichnung: CDO1 (CDO1 Produkte)

Synonyme: 1300002L19Rik antikoerper, Cdo antikoerper, D18Ucla3 antikoerper, cysteine dioxygenase, type I antikoerper, cysteine dioxygenase 1, cytosolic antikoerper, cysteine dioxygenase type 1 antikoerper, NAEGRDRAFT_80458 antikoerper, Cdo1 antikoerper, CDO1 antikoerper

Hintergrund:

CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94 % amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis, taurine biosynthesis, hypotaurine from L-cysteine: step 1/2.

Subcellular location: Cytoplasm

Synonyms: Cysteine Dioxygenase Type 1, CDO 1, CDO, CDO I, CDO1, CDO-1, CDOI, Cytosolic cysteine dioxygenase, CDO1_HUMAN.

Gen-ID: 1036