CCR7 Antikörper (PE-Cy5.5)

Produktnummer ABIN888638

Der Kaninchen Polyklonal Anti-CCR7-Antikörper wurde für FACS und WB validiert. Er ist geeignet, CCR7 in Proben von Human, Maus, Ratte und Hund zu detektieren.

Kurzübersicht für CCR7 Antikörper (PE-Cy5.5) (ABIN888638)

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR7 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS), Western Blotting (WB)

Produktdetails anti-CCR7 Antikörper (PE-Cy5.5)

Kreuzreaktivität: Human, Maus, Ratte, Schaf

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCR7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Andere Bezeichnung: CCR7/CD197

Hintergrund:

Synonyms: EBI1, CCR-7, CD197, Ebi1h, Cdw197, Cmkbr7, CC-CKR-7, C-C chemokine receptor type 7, C-C CKR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, Ccr7

Background: CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.

Molekulargewicht: 42kDa

Gen-ID: 12775

UniProt: P47774

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process