CCDC43 Antikörper (AA 151-224) (Cy7)

Produktnummer ABIN887744

Der Kaninchen Polyklonal Anti-CCDC43-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CCDC43 in Proben von Human zu detektieren.

Kurzübersicht für CCDC43 Antikörper (AA 151-224) (Cy7) (ABIN887744)

Target: CCDC43 (Coiled-Coil Domain Containing 43 (CCDC43))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC43 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CCDC43 Antikörper (Cy7)

Bindungsspezifität: AA 151-224

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC43

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC43

Target: CCDC43 (Coiled-Coil Domain Containing 43 (CCDC43))

Andere Bezeichnung: CCDC43

Hintergrund:

Synonyms: CCDC 43, Coiled coil domain containing 43, coiled coil domain containing protein 43, FLJ31795, CCD43_HUMAN.

Background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC43 (coiled-coil domain containing 43) is a 224 amino acid protein encoded by a gene that maps to human chromosome 17q21.31. Encoding over 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Gen-ID: 124808