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CCDC40 Antikörper (AA 851-950) (Alexa Fluor 488)

CCDC40 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN887711
  • Target Alle CCDC40 Antikörper anzeigen
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Bindungsspezifität
    • 14
    • 1
    AA 851-950
    Reaktivität
    Human
    Wirt
    • 15
    • 1
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC40 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC4
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC40 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Andere Bezeichnung
    CCDC40 (CCDC40 Produkte)
    Synonyme
    CILD15 antikoerper, B930008I02Rik antikoerper, im:7149866 antikoerper, lok antikoerper, si:dkey-237i9.5 antikoerper, wu:fb11d02 antikoerper, coiled-coil domain containing 40 antikoerper, CCDC40 antikoerper, Ccdc40 antikoerper, ccdc40 antikoerper
    Hintergrund

    Synonyms: CCD40_HUMAN, ccdc 40, CCDC40, Coiled coil domain containing 40, coiled-coil domain containing 40, Coiled-coil domain-containing protein 40.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    Gen-ID
    55036
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