CCDC39 Antikörper (Cy5)

Produktnummer ABIN887697

Dieses Anti-CCDC39-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCDC39 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CCDC39 Antikörper (Cy5) (ABIN887697)

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC39 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB)

Produktdetails anti-CCDC39 Antikörper (Cy5)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC39

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC39

Target: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Andere Bezeichnung: Ccdc39

Hintergrund:

Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

Gen-ID: 339829