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CCDC17 Antikörper (AA 351-450) (FITC)

Dieses Anti-CCDC17-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCDC17 in IF (cc) und IF (p). Geeignet für Ratte.
Produktnummer ABIN887463

Kurzübersicht für CCDC17 Antikörper (AA 351-450) (FITC) (ABIN887463)

Target

Alle CCDC17 Antikörper anzeigen
CCDC17 (Coiled-Coil Domain Containing 17 (CCDC17))

Reaktivität

  • 17
  • 15
  • 1
Ratte

Wirt

  • 31
Kaninchen

Klonalität

  • 31
Polyklonal

Konjugat

  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCDC17 Antikörper ist konjugiert mit FITC

Applikation

  • 14
  • 14
  • 12
  • 12
  • 9
  • 7
  • 6
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 351-450

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CCDC17

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CCDC17 (Coiled-Coil Domain Containing 17 (CCDC17))

    Andere Bezeichnung

    CCDC17

    Hintergrund

    Synonyms: CCD17_HUMAN, CCDC17, Coiled coil domain containing 17, Coiled-coil domain-containing protein 17, RP23-233B9.8, RP4-697E16.4.

    Background: CCDC17, also known as FLJ17921 or RP4-697E16.4, is a 622 amino acid protein expressed as four isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

    Gen-ID

    149483
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