CCDC148 Antikörper (AA 401-500) (Cy3)

Produktnummer ABIN887328

Dieses Anti-CCDC148-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCDC148 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für CCDC148 Antikörper (AA 401-500) (Cy3) (ABIN887328)

Target: CCDC148 (Coiled-Coil Domain Containing 148 (CCDC148))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC148 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CCDC148 Antikörper (Cy3)

Bindungsspezifität: AA 401-500

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC148

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC148

Target: CCDC148 (Coiled-Coil Domain Containing 148 (CCDC148))

Andere Bezeichnung: CCDC148

Hintergrund:

Synonyms: CCDC 148, coiled coil domain containing 148, coiled-coil domain containing 148, CC148_HUMAN.

Background: CCDC148 (coiled-coil domain containing 148), also known as MGC125590 or MGC125588, is a 591 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.