CCDC112 Antikörper (AA 301-400) (Alexa Fluor 488)

Produktnummer ABIN887002

Produktdetails anti-CCDC112 Antikörper

Target: CCDC112 (Coiled-Coil Domain Containing 112 (CCDC112))

Bindungsspezifität: AA 301-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC112 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC112/MBC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu CCDC112

Target: CCDC112 (Coiled-Coil Domain Containing 112 (CCDC112))

Andere Bezeichnung: MBC1 (CCDC112 Produkte)

Synonyme: CCDC112 antikoerper, RGD1561942 antikoerper, MBC1 antikoerper, 8430438M01Rik antikoerper, AW108467 antikoerper, coiled-coil domain containing 112 antikoerper, CCDC112 antikoerper, Ccdc112 antikoerper, ccdc112 antikoerper

Hintergrund:

CCDC112, also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6 % of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome

Subcellular location: Cytoplasm, Nucleus, Secreted, Cell membrane, Extracellular matrix

Synonyms: MBC1, Mutated in bladder cancer protein 1, coiled coil domain containing 112, coiled-coil domain containing 112, MBC1, CC112_HUMAN.

Gen-ID: 153733