CARD14 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN886391

Der Kaninchen Polyklonal Anti-CARD14 Antikörper wurde für ELISA, WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, CARD14 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CARD14 Antikörper (AA 1-100) (Biotin) (ABIN886391)

Target: CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD14 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CARD14 Antikörper (Biotin)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CARD14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CARD14

Target: CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))

Andere Bezeichnung: CARD14

Hintergrund:

Synonyms: Bcl10 interacting MAGUK protein 2, Bimp 2, Bimp2, CARD 14, CARD containing MAGUK 2 protein, CARD containing MAGUK protein 2, Card maguk protein 2, Carma 2, Carma2, Caspase recruitment domain containing protein 14, Caspase recruitment domain family member 14, Caspase recruitment domain protein 14, CAR14_HUMAN.

Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Gen-ID: 79092