Attractin Antikörper (AA 751-850) (AbBy Fluor® 555)

Produktnummer ABIN884123

Der Kaninchen Polyklonal Anti-Attractin-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, Attractin in Proben von Human und Maus zu detektieren.

Kurzübersicht für Attractin Antikörper (AA 751-850) (AbBy Fluor® 555) (ABIN884123)

Target: Attractin (ATRN)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Attractin Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Attractin Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 751-850

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATRN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Attractin

Target: Attractin (ATRN)

Andere Bezeichnung: Atrn

Hintergrund:

Synonyms: ATRN, attractin-2, DPPT-L, KIAA0548, Mahogany homolog, mahogany protein, MGCA.

Background: Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.

Gen-ID: 8455