ALAD Antikörper (AA 151-240) (HRP)

Produktnummer ABIN882114

Dieses Anti-ALAD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALAD in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Maus.

Kurzübersicht für ALAD Antikörper (AA 151-240) (HRP) (ABIN882114)

Target: ALAD (Aminolevulinate Dehydratase (ALAD))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAD Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ALAD Antikörper (HRP)

Bindungsspezifität: AA 151-240

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ALAD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ALAD

Target: ALAD (Aminolevulinate Dehydratase (ALAD))

Andere Bezeichnung: ALAD

Hintergrund:

Synonyms: ALAD, ALADH, ALADR, Aminolevulinate dehydratase, Aminolevulinate, delta, dehydratase, Delta aminolevulinic acid dehydratase, Delta-aminolevulinic acid dehydratase, HEM2_HUMAN, Lv, PBGS, Porphobilinogen synthase.

Background: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP). AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.

Gen-ID: 210

UniProt: P13716