HMGCR Antikörper (pSer872) (AbBy Fluor® 555)
Kurzübersicht für HMGCR Antikörper (pSer872) (AbBy Fluor® 555) (ABIN877207)
Target
Alle HMGCR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer872
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Spezifität
- This phosphorylation site is homologous to that of Ser871 in Mouse and Rat.
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Dog,Cow,Pig,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human HMGCR around the phosphorylation site of Ser872
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Isotyp
- IgG
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Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
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Andere Bezeichnung
- HMGCR
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Hintergrund
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Synonyms: LDLCQ3, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, HMGCR, phospho HMGCR, p-HMGCR
Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
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Gen-ID
- 3156
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UniProt
- P04035
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Pathways
- AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
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