PML Antikörper (pSer19) (AbBy Fluor® 647)

Produktnummer ABIN874649

Der Kaninchen Polyklonal Anti-PML-Antikörper wurde für IF (p) validiert. Er ist geeignet, PML in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PML Antikörper (pSer19) (AbBy Fluor® 647) (ABIN874649)

Target: PML (Promyelocytic Leukemia (PML))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PML Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PML Antikörper (AbBy Fluor® 647)

Bindungsspezifität: pSer19

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MYL2 around the phosphorylation site of Ser19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu PML

Target: PML (Promyelocytic Leukemia (PML))

Andere Bezeichnung: Myl

Hintergrund:

Myosin light chain (MLC) is a subunit of the conventional myosins (e.g. myosin II). In smooth muscle and non-muscle cells conventional myosins mediate a wide variety of contractile events including cytokinesis, cell motility, and smooth muscle contraction. MLC is phosphorylated by multiple serine-threonine kinases such as Rho-kinase and PAK, however myosin light chain kinase (MLCK) acts as the primary kinase. Contractile activity of conventional myosins is regulated by phosphorylation of MLC on several residues.

Synonyms: Cardiac myosin light chain-2, Cardiac ventricular myosin light chain 2, CMH10, MLC 2v, MLC2, MYL 2, Myosin light chain 2 regulatory cardiac slow, Myosin light polypeptide 2 regulatory cardiac slow, Myosin regulatory light chain 2 ventricular cardiac muscle isoform, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, Regulatory light chain of myosin, RLC of myosin, Slow cardiac myosin regulatory light chain 2.MLRV_HUMAN

Gen-ID: 5371

Pathways: p53 Signalweg, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus