SNCA Antikörper (pSer129) (AbBy Fluor® 350)

Produktnummer ABIN874194

Dieses Anti-SNCA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNCA in WB, IF (p), IF (cc) und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SNCA Antikörper (pSer129) (AbBy Fluor® 350) (ABIN874194)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNCA Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Produktdetails anti-SNCA Antikörper (AbBy Fluor® 350)

Bindungsspezifität: pSer129

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SNCA around the phosphorylation site of Ser129 [MP(p-S)EE]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: Alpha synuclein

Hintergrund:

Synonyms: SNCAphospho S129, alpha Synuclein phospho S129 ,alpha-Synuclein Ser129, Synuclein alphaSer129, Alpha synuclein, Alpha-Synuclein, Alpha-synuclein, isoform NACP140, alpha SYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid , precursor of, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease autosomal dominant, Lewy body 4, Parkinson disease familial 1, PD 1, PD1, Syn, SNCA, Snca synuclein, alpha non A4 component of amyloid precursor, SYUA_HUMAN, Synuclein alpha, Synuclein, alpha non A4 component of amyloid precursor,

Background: The synucleins, including Alpha-synuclein (also designated NACP for nonamyloid component precursor),Beta-synuclein (also designated PNP 14 for neuroprotein 14)and Gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. Alpha-synuclein, a component of Alzheimer?s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of Alpha-synucleinand Beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson?s disease, a mutant form of Alpha-synuclein has been found and Gamma-synuclein is associated with axonal pathology.

Gen-ID: 6622

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity