CCDC116 Antikörper (AA 155-260)

Produktnummer ABIN873296

Der Kaninchen Polyklonal Anti-CCDC116-Antikörper wurde für ELISA, WB, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, CCDC116 in Proben von Human zu detektieren.

Kurzübersicht für CCDC116 Antikörper (AA 155-260) (ABIN873296)

Target: CCDC116 (Coiled-Coil Domain Containing 116 (CCDC116))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC116 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CCDC116 Antikörper

Bindungsspezifität: AA 155-260

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC116

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC116

Target: CCDC116 (Coiled-Coil Domain Containing 116 (CCDC116))

Andere Bezeichnung: CCDC116

Hintergrund:

Synonyms: CC116_HUMAN, Ccdc116, Coiled-coil domain-containing protein 116.

Background: CCDC116 is a 515 amino acid protein that exists as two alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 22q11.21, CCDC116 is induced by curcumin (diferulolylmethane), although its role is unclear. CCDC116 is significantly affected by dietary curcumin, which may have a protective role in inflammatory bowel disease (IBD) and may reduce the relapse rate in human ulcerative colitis (UC). As the second smallest human chromosome, chromosome 22 contains over 500 genes and about 49 million bases. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocation between chromosomes 9 and 22 may lead to the formation of Philadelphia Chromosome and subsequent production of a novel fusion protein known as BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

Gen-ID: 164592