COMMD7 Antikörper (AA 81-170)

Produktnummer ABIN873293

Der Kaninchen Polyklonal anti-COMMD7 Antikörper wird verwendet zum Nachweis von COMMD7 in Proben von Human. Er wurde validiert für IHC (p), IF (cc), IF (p) und IHC (fro).

Kurzübersicht für COMMD7 Antikörper (AA 81-170) (ABIN873293)

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COMMD7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-COMMD7 Antikörper

Bindungsspezifität: AA 81-170

Verwendungszweck: COMMD7 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu COMMD7

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Andere Bezeichnung: COMMD7

Hintergrund:

Synonyms: C20orf92, Chromosome 20 open reading frame 92, COMM domain containing 7, COMM domain containing protein 7, COMMD 7, dJ1085F17.3, FLJ14987, MGC33315, OTTHUMP00000030609, COMD7_HUMAN.

Background: COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity.

Gen-ID: 149951