ASMT Antikörper

Produktnummer ABIN873275

Der Kaninchen Polyklonal Anti-ASMT-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, ASMT in Proben von Human, Maus und Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für ASMT Antikörper (ABIN873275)

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ASMT Antikörper

Kreuzreaktivität: Ratte, Schaf

Homologie: Human,Mouse,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ASMT Antikörper (ABIN873275)

Herman, Bochenek, Król, Krawczyńska, Antushevich, Pawlina, Herman, Romanowicz, Tomaszewska-Zaremba: "Central Interleukin-1�� Suppresses the Nocturnal Secretion of Melatonin." in: Mediators of inflammation, Vol. 2016, pp. 2589483, (2017) (PubMed).

Herman, Wojtulewicz, Bochenek, Krawczyńska, Antushevich, Pawlina, Zielińska-Górska, Herman, Romanowicz, Tomaszewska-Zaremba: "Endotoxin-induced inflammation disturbs melatonin secretion in ewe." in: Asian-Australasian journal of animal sciences, Vol. 30, Issue 12, pp. 1784-1795, (2017) (PubMed).

Herman, Bochenek, Skipor, Król, Krawczyńska, Antushevich, Pawlina, Marciniak, Tomaszewska-Zaremba: "Interleukin-1 β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study." in: BioMed research international, Vol. 2015, pp. 526464, (2016) (PubMed).

Details zu ASMT

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Andere Bezeichnung: Asmt

Hintergrund:

Synonyms: Acetylserotonin O-methyltransferase, ASMT, ASMTY, HIOMT, HIOMTY, Hydroxyindole O-methyltransferase.

Background: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity

Gen-ID: 438

UniProt: P46597