Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FGA Antikörper (AA 61-160)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FGA in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Ratte und Maus und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN873232

Kurzübersicht für FGA Antikörper (AA 61-160) (ABIN873232)

Target

Alle FGA Antikörper anzeigen
FGA (Fibrinogen alpha Chain (FGA))

Reaktivität

  • 59
  • 41
  • 27
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Ratte, Maus

Wirt

  • 75
  • 21
  • 6
  • 2
Kaninchen

Klonalität

  • 80
  • 24
Polyklonal

Konjugat

  • 59
  • 14
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGA Antikörper ist unkonjugiert

Applikation

  • 83
  • 47
  • 27
  • 27
  • 21
  • 15
  • 12
  • 12
  • 9
  • 9
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Imamura, Yamada, Tsuboi, Nakane, Tsukasaki, Komatsuzaki, Jin: "Near-Infrared Emitting PbS Quantum Dots for in Vivo Fluorescence Imaging of the Thrombotic State in Septic Mouse Brain." in: Molecules (Basel, Switzerland), Vol. 21, Issue 8, (2016) (PubMed).

    Li, He, Di, Yan, Zhang: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." in: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).

  • Target

    FGA (Fibrinogen alpha Chain (FGA))

    Andere Bezeichnung

    Fibrinogen alpha chain

    Hintergrund

    Synonyms: Fib2, Fibrinogen alpha chain, FGA, Fibrin

    Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

    Gen-ID

    2243

    UniProt

    P02671
Sie sind hier:
Chat with us!