NOC2L Antikörper (AA 251-350)

Produktnummer ABIN873201

Dieses Anti-NOC2L-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOC2L in ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für NOC2L Antikörper (AA 251-350) (ABIN873201)

Target: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOC2L Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NOC2L Antikörper

Bindungsspezifität: AA 251-350

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOC2L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NOC2L

Target: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Andere Bezeichnung: NOC2L

Hintergrund:

Synonyms: NIR, NOC2 like, Novel INHAT inhibitor of histone acetyltransferase repressor, Nucleolar complex associated 2 homolog S. cerevisiae, Protein NOC2 homolog, NOC2L_HUMAN.

Background: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.

Gen-ID: 26155

Pathways: Negative Regulation of intrinsic apoptotic Signaling